Postdoctoral Fellow: Mathematical Modeling of Nanoparticle/Cell Interaction.
We are seeking a highly motivated scientist to join a collaborative team of basic and translational research scientists interested in the application of nanotechnology to biomedical sciences. The team involves multiple investigators from The University of Texas Health Science Center – Houston; The University of Texas MD Anderson Cancer Center; Rice University and Baylor College of Medicine, four leading institutions in the Texas Medical Center, with the aim of unraveling the biological and biophysical mechanisms regulating the cellular internalization and intracellular trafficking of nanoparticles to be used for the delivery of therapeutic and imaging agents.

The successful applicant will develop new multiscale mathematical models and improve existing software for studying the internalization behavior of nanoparticles as a function of their size, shape and surface properties. He/She will work in close collaboration with experimentalists (tumor and vascular biologists, physicists and chemists) to validate/refine the mathematical models and help in designing new experiments and in-vitro assays. The research activity will be developed in the newly established Dept. of Nanomedicine and Biomedical Engineering within the Medical School of The University of Texas Health Science Center – Houston.

A PhD in Biomedical/Mechanical/Chemical Engineering, Physics, Material Science, Theoretical Biology or a related field, exceptional scholarly record, intellectual maturity and independence as well as excellent teamwork and communications skills are required. Substantial expertise in particle methods (Molecular Dynamics, Dissipative Particle Dynamics,…) and in developing hybrid Particle/Continuum models is highly desired.

To apply, send a CV, a one-page research statement, and names of three referees to Prof. Paolo Decuzzi at Paolo.Decuzzi@uth.tmc.edu. The review of applications will begin immediately.

Postdoctoral Fellow: Modeling the Transport of Nanoparticles in the Authentic Vasculature.
We are seeking a highly motivated scientist to join a collaborative team of basic and translational research scientists interested in the application of nanotechnology to biomedical sciences. The team involves multiple investigators from The University of Texas Health Science Center – Houston; The University of Texas MD Anderson Cancer Center; Rice University; The University of Texas at Austin and Harvard Medical School with the aim of studying alterations in multi-scale transport in solid tumors. This activity will fall within the research initiative on “PS-OC” (Physical Sciences in Oncology) recently launched by the US National Cancer Institute.

The successful applicant will develop new multiscale mathematical models and improve existing software for studying the dynamics of nanoparticles in the authentic vasculature as a function of their size, shape and surface properties. He/She will work in close collaboration with experimentalists (vascular biologists, physicists, chemists) to validate/refine the mathematical models and help in designing new experiments. The research activity will be developed in the newly established Dept. of Nanomedicine and Biomedical Engineering within the Medical School of The University of Texas Health Science Center – Houston.

A PhD in Biomedical/Mechanical/Chemical Engineering, Theoretical Biology or a related field, exceptional scholarly record, intellectual maturity and independence as well as excellent teamwork and communications skills are required. Substantial expertise in developing hybrid models (Particle-based/Continuum mechanics) for fluid flow and mass transport is strongly desired. Expertise in imaging analysis and geometric reconstruction will be also considered.

To apply, send a CV, a one-page research statement, and names of three referees to Prof. Paolo Decuzzi at Paolo.Decuzzi@uth.tmc.edu. The review of applications will begin immediately.

Postdoctoral fellow positions (new graduates or experienced):
We are seeking enthusiastic candidates at different levels who are interested in developing novel diagnostic and therapeutic methods to treat cancer, cardiovascular disease and other human diseases using nanotechnology. The successful candidate must have expertise and experience in the specified areas and be willing to work as a team member in a multi-disciplinary and fast-paced environment. Please send resume to freddie.fegans@uth.tmc.edu.

Postdoctoral Fellow 1: Expert in Hemorrhagic Conditions
We are seeking a highly motivated scientist to join an intensely collaborative team of basic and translational research scientists interested in application of nanotechnology to fields related to blood coagulation research, encompassing vascular biology, hemostasis, hemorrhagic and thrombotic conditions across a broad spectrum of vascular disorders and in the development of strategies, methods, or nanotechnology based treatments. Specific areas of interest include blood coagulation reaction mechanisms, biochemical/biophysical/x-ray structural characterizations of protein-protein, and protein-membrane interactions, dynamics and proteomics of the blood coagulation/fibrinolytic systems, platelet/megakaryocyte biology. Experience in the fields of platelets structure function, biosynthesis of cellular components and cellular metabolism, and mechanisms of enzyme action, regulation, activation and inhibition as well as of animal models of thrombotic and hemorrhagic conditions is desirable.

Successful applicants will work in a well-funded lab that is located at the University of Texas Health Science Center at Houston. The lab focuses on clinical applications of nanotechnology and translational research. Motivated applicants with a PhD in cellular and molecular biology, biomedical engineering, or a related field are encouraged to apply. The ideal applicant will be able to work independently, supervise others in the lab, and be highly skilled in lab techniques. Please send resume to tong.sun@uth.tmc.edu

Postdoctoral Fellow in the Department of Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center
The Alliance for Nanohealth at Houston invites applications for postdoctoral fellows in nanotechnology and imaging sciences. Specific research topic includes development of multi-stage nanostructures for cancer diagnosis and therapy, and nanodevices for imaging treatment responses. Candidates should posses a PhD degree in material science or biomedical engineering. Experiences in the synthesis and characterization of nanomaterials are required. A combination of skills in molecular imaging and relevant analytical methods (e.g. HPLC, NMR, MS, TEM) will be a plus. Send resume and names of 3 references to: Dr. Chun Li, Department of Experimental Diagnostic Imaging, Box 59, U. T. M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas, 77030; e-mail: cli@mdanderson.org. The University of Texas M. D. Anderson Cancer Center is an equal opportunity employer. Smoke-free and drug-free environment.

Students:

1. We have open positions for Ph.D. graduate students looking for tutorial or thesis research opportunities in cancer biology, biochemistry, biomedical engineering, computer science and mathematical modeling, mechanical engineering.

2. We have open position for undergraduate students to work as summer interns in mechanical engineering, biomedical engineering, chemistry and biology.

Please send resume to freddie.fegans@uth.tmc.edu.

Research Assistant Sr. - Animal Study Coordinator (experienced candidates with a Bachelor degree at minimum, Master degree preferred):
Designs, organizes, executes, and interprets the results of complex in vivo experiments with experimental animals with a focus in mice and rats. Performs limited bench work and cell culture. Serves as a lead in animal research in the Division of Nanomedicine. Designs, organizes, executes, and interprets the results of complex in vivo experiments with experimental animals with a focus in mice and rats. Performs limited bench work and cell culture. Serves as a lead in animal research in the Division of Nanomedicine. Apply here.